The Montreal Cognitive Assessment as a screening tool for cognitive dysfunction in Huntington's disease
Identifieur interne : 001974 ( Main/Exploration ); précédent : 001973; suivant : 001975The Montreal Cognitive Assessment as a screening tool for cognitive dysfunction in Huntington's disease
Auteurs : Aleksandar Videnovic [États-Unis] ; Bryan Bernard [États-Unis] ; Wenqing Fan [États-Unis] ; Jeana Jaglin [États-Unis] ; Sue Leurgans [États-Unis] ; Kathleen M. Shannon [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2010-02-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adult, Aged, Cognition, Cognition Disorders (diagnosis), Cognition Disorders (etiology), Cognitive disorder, Disability Evaluation, Female, Humans, Huntington Disease (complications), Huntington disease, Huntington's disease, MMSE, Male, Mass Screening (methods), Medical screening, Mental Status Schedule, Middle Aged, MoCA, Nervous system diseases, Neuropsychological Tests, cognition.
- MESH :
- complications : Huntington Disease.
- diagnosis : Cognition Disorders.
- etiology : Cognition Disorders.
- methods : Mass Screening.
- Adult, Aged, Disability Evaluation, Female, Humans, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests.
Abstract
Cognitive dysfunction is one of the hallmarks of Huntington's disease (HD) and may precede the onset of motor symptoms. The Montreal Cognitive Assessment (MoCA), a brief cognitive screening instrument with high specificity and sensitivity for detecting early cognitive impairments, has not been studied in the HD population. In this study, we compare the MoCA with the mini‐mental state examination (MMSE) as a screening tool for cognitive dysfunction among 53 patients with HD. The mean MMSE score was 26 ± 2.4, and mean MoCA score was 21 ± 4.4. Twenty‐one patients (81%) of those who scored ≥26 on the MMSE had the MoCA score <26. Thirty‐two patients (78%) of those who scored ≥24 on the MMSE had the MoCA score <24. The MoCA may be a more sensitive screening tool for cognitive impairments in HD relative to the MMSE. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.22748
Affiliations:
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The Montreal Cognitive Assessment (MoCA), a brief cognitive screening instrument with high specificity and sensitivity for detecting early cognitive impairments, has not been studied in the HD population. In this study, we compare the MoCA with the mini‐mental state examination (MMSE) as a screening tool for cognitive dysfunction among 53 patients with HD. The mean MMSE score was 26 ± 2.4, and mean MoCA score was 21 ± 4.4. Twenty‐one patients (81%) of those who scored ≥26 on the MMSE had the MoCA score <26. Thirty‐two patients (78%) of those who scored ≥24 on the MMSE had the MoCA score <24. The MoCA may be a more sensitive screening tool for cognitive impairments in HD relative to the MMSE. © 2010 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Illinois</li></region></list><tree><country name="États-Unis"><region name="Illinois"><name sortKey="Videnovic, Aleksandar" sort="Videnovic, Aleksandar" uniqKey="Videnovic A" first="Aleksandar" last="Videnovic">Aleksandar Videnovic</name></region><name sortKey="Bernard, Bryan" sort="Bernard, Bryan" uniqKey="Bernard B" first="Bryan" last="Bernard">Bryan Bernard</name><name sortKey="Fan, Wenqing" sort="Fan, Wenqing" uniqKey="Fan W" first="Wenqing" last="Fan">Wenqing Fan</name><name sortKey="Jaglin, Jeana" sort="Jaglin, Jeana" uniqKey="Jaglin J" first="Jeana" last="Jaglin">Jeana Jaglin</name><name sortKey="Leurgans, Sue" sort="Leurgans, Sue" uniqKey="Leurgans S" first="Sue" last="Leurgans">Sue Leurgans</name><name sortKey="Shannon, Kathleen M" sort="Shannon, Kathleen M" uniqKey="Shannon K" first="Kathleen M." last="Shannon">Kathleen M. 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